Mrs. Stancliffe's Rose Cottage Bed & Breakfast has been successful for many years because her guests (nearly all women) return year after year. Her next door neighbor, the elderly, silver-tongued "Bud the Stud" Davis, believes they come to spend time with him in romantic liaisons. The prim and proper Mrs. Stancliffe steadfastly denies this, but reluctantly accepts the fact that "Bud the Stud" is good for business. Her other neighbor and would-be suitor, Henry Mitchell, is a retired chemist who has developed a blue pill called "Venusia" to increase the libido of menopausal women. The pill has not been tested until Bud gets his hands on some and the fun begins. The women mix up Bud's other pills with the Venusia, and we soon discover that it has a strange effect on men: it gives them all the symptoms of menopause, complete with hot flashes, mood swings, weeping and irritability! When the mayhem settles down, all the women find their lives moving in new and surprising directions.